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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
22.73
Human Site:
S562
Identified Species:
38.46
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
S562
G
V
P
A
E
G
L
S
R
S
Y
S
R
P
S
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S562
G
V
P
A
E
G
L
S
R
S
Y
S
R
P
S
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
S568
G
V
P
A
E
G
L
S
R
S
Y
S
R
P
S
Dog
Lupus familis
XP_538417
666
74288
S567
G
A
P
P
E
G
L
S
R
S
Y
S
R
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
S563
G
V
P
S
D
G
I
S
R
S
Y
S
R
P
S
Rat
Rattus norvegicus
Q66HE5
630
69934
R541
A
S
P
H
P
T
A
R
A
S
R
P
S
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
S562
V
G
P
G
D
G
L
S
R
S
Y
S
R
P
S
Chicken
Gallus gallus
Q9IA88
798
88848
V554
S
D
A
P
V
L
Q
V
Q
G
C
M
G
G
A
Frog
Xenopus laevis
NP_001088596
570
64876
S481
S
S
S
I
S
Q
E
S
I
L
S
T
E
S
F
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
Q884
Y
G
G
P
S
A
L
Q
Q
A
L
L
S
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
S1185
M
S
Q
A
T
I
T
S
T
S
Q
P
I
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
P728
S
K
L
I
N
K
T
P
A
A
G
G
T
A
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
K422
Q
E
L
N
V
C
W
K
K
I
G
H
Y
N
M
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
L541
A
K
P
S
E
E
D
L
W
T
I
K
L
R
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
13.3
N.A.
73.3
0
6.6
13.3
N.A.
20
N.A.
0
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
20
N.A.
80
13.3
13.3
33.3
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
29
0
8
8
0
15
15
0
0
0
8
22
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
0
15
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
36
8
8
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
36
15
8
8
0
43
0
0
0
8
15
8
8
15
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
15
0
8
8
0
8
8
8
0
8
0
0
% I
% Lys:
0
15
0
0
0
8
0
8
8
0
0
8
0
8
8
% K
% Leu:
0
0
15
0
0
8
43
8
0
8
8
8
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
58
22
8
0
0
8
0
0
0
15
0
50
0
% P
% Gln:
8
0
8
0
0
8
8
8
15
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
43
0
8
0
43
8
0
% R
% Ser:
22
22
8
15
15
0
0
58
0
58
8
43
15
8
43
% S
% Thr:
0
0
0
0
8
8
15
0
8
8
0
8
8
0
8
% T
% Val:
8
29
0
0
15
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
43
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _